引用本文:
Gu He, Li Guo. Synthesis and theoretical study of first generation CCK-functional dendrimers[J]. Chinese Chemical Letters,
2007, 18(12): 1505-1508.
doi:
10.1016/j.cclet.2007.10.004
Citation: Gu He, Li Guo. Synthesis and theoretical study of first generation CCK-functional dendrimers[J]. Chinese Chemical Letters, 2007, 18(12): 1505-1508. doi: 10.1016/j.cclet.2007.10.004
Citation: Gu He, Li Guo. Synthesis and theoretical study of first generation CCK-functional dendrimers[J]. Chinese Chemical Letters, 2007, 18(12): 1505-1508. doi: 10.1016/j.cclet.2007.10.004
Synthesis and theoretical study of first generation CCK-functional dendrimers
摘要:
A convenient synthesis and theoretical study of five CCK-functional dendrimers is described. The dendritic cores were linked with the CCK (Trp-Met-Asp (OBn)-PheNH2) fragment by forming amide bonds to give five target molecules. The structures of CCK-functional dendrimers were characterized by NMR, MS spectrum and predicted using molecular mechanics and PM3 semiempirical molecular orbital theory.
English
Synthesis and theoretical study of first generation CCK-functional dendrimers
Abstract:
A convenient synthesis and theoretical study of five CCK-functional dendrimers is described. The dendritic cores were linked with the CCK (Trp-Met-Asp (OBn)-PheNH2) fragment by forming amide bonds to give five target molecules. The structures of CCK-functional dendrimers were characterized by NMR, MS spectrum and predicted using molecular mechanics and PM3 semiempirical molecular orbital theory.
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Key words:
- Dendrimer
- / CCK
- / Synthesis
- / Molecular mechanics
- / Semi-empirical molecular orbital theory
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