引用本文:
Cherkupally Sanjeeva Reddy, Adki Nagaraj. Knoevenagel condensation of α,β-unsaturated aromatic aldehydes with barbituric acid under non-catalytic and solvent-free conditions[J]. Chinese Chemical Letters,
2007, 18(12): 1431-1435.
doi:
10.1016/j.cclet.2007.10.016
Citation: Cherkupally Sanjeeva Reddy, Adki Nagaraj. Knoevenagel condensation of α,β-unsaturated aromatic aldehydes with barbituric acid under non-catalytic and solvent-free conditions[J]. Chinese Chemical Letters, 2007, 18(12): 1431-1435. doi: 10.1016/j.cclet.2007.10.016
Citation: Cherkupally Sanjeeva Reddy, Adki Nagaraj. Knoevenagel condensation of α,β-unsaturated aromatic aldehydes with barbituric acid under non-catalytic and solvent-free conditions[J]. Chinese Chemical Letters, 2007, 18(12): 1431-1435. doi: 10.1016/j.cclet.2007.10.016
Knoevenagel condensation of α,β-unsaturated aromatic aldehydes with barbituric acid under non-catalytic and solvent-free conditions
摘要:
An efficient route for the synthesis of 5-(arylpropenylidine)-2, 4, 6-pyrimidinetrione 3 from an appropriate α, β-unsaturated aromatic aldehydes 1 and barbituric acid 2 under both non-catalytic and solvent-free microwave irradiation conditions was described. In this way, a range of biologically important compounds 3 was obtained in good to excellent yields (86-98%) in a very short reaction time (30-80 s).
English
Knoevenagel condensation of α,β-unsaturated aromatic aldehydes with barbituric acid under non-catalytic and solvent-free conditions
Abstract:
An efficient route for the synthesis of 5-(arylpropenylidine)-2, 4, 6-pyrimidinetrione 3 from an appropriate α, β-unsaturated aromatic aldehydes 1 and barbituric acid 2 under both non-catalytic and solvent-free microwave irradiation conditions was described. In this way, a range of biologically important compounds 3 was obtained in good to excellent yields (86-98%) in a very short reaction time (30-80 s).
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