Interaction between Bifunctional Dioxo Macrocyclic Polyamine Co(Ⅱ) Complex and DNA in Metallomicellar System

Qing Xiang XIANG Hong ZHOU Xin Yan WANG Xiao Qi YU Jing Ku BAO Ru Gang XIE

引用本文: Qing Xiang XIANG,  Hong ZHOU,  Xin Yan WANG,  Xiao Qi YU,  Jing Ku BAO,  Ru Gang XIE. Interaction between Bifunctional Dioxo Macrocyclic Polyamine Co(Ⅱ) Complex and DNA in Metallomicellar System[J]. Chinese Chemical Letters, 2002, 13(3): 223-226. shu
Citation:  Qing Xiang XIANG,  Hong ZHOU,  Xin Yan WANG,  Xiao Qi YU,  Jing Ku BAO,  Ru Gang XIE. Interaction between Bifunctional Dioxo Macrocyclic Polyamine Co(Ⅱ) Complex and DNA in Metallomicellar System[J]. Chinese Chemical Letters, 2002, 13(3): 223-226. shu

Interaction between Bifunctional Dioxo Macrocyclic Polyamine Co(Ⅱ) Complex and DNA in Metallomicellar System

  • 基金项目:

    We are thankful to the National Natural Science Foundation of China for financial support (No. 29872027).

摘要: The cleavage of DNA (pUC18) by lipophilic macrocyclic polyamine Co(Ⅱ) complex was investigated in metallomicellar system. The results showed that the conversion of plasmid DNA (pUC18) increases with the increase of the concentration of complex under physiological conditions.

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  • 收稿日期:  2001-07-06
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