A novel synthesis of 5-aryl-3-cyano-2-pyridones by using vinamidinium salts

Xue Hui Zhang ,  Wu Zhong ,  Xing Zhou Li ,  Song Li

引用本文: Xue Hui Zhang,  Wu Zhong,  Xing Zhou Li,  Song Li. A novel synthesis of 5-aryl-3-cyano-2-pyridones by using vinamidinium salts[J]. Chinese Chemical Letters, 2009, 20(7): 771-774. doi: 10.1016/j.cclet.2009.02.016 shu
Citation:  Xue Hui Zhang,  Wu Zhong,  Xing Zhou Li,  Song Li. A novel synthesis of 5-aryl-3-cyano-2-pyridones by using vinamidinium salts[J]. Chinese Chemical Letters, 2009, 20(7): 771-774. doi: 10.1016/j.cclet.2009.02.016 shu

A novel synthesis of 5-aryl-3-cyano-2-pyridones by using vinamidinium salts

  • 基金项目:

    This work was supported by the National Basic Research Program of China (No.2004CB518908) and the National High Technology Research and Development Program of China (No.2006AA020601).

摘要: A variety of vinamidinium salts were condensated with cyanoacetamide in refluxing methanol that contained sodium methoxide to produce 5-aryl-3-cyano-2-pyridones in good yield. Simple experimental conditions were used to prepare ten different 5-aryl-3-cyano-2-pyridones, four of which are new compounds.

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  • 收稿日期:  2008-12-15
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