Citation:
QU Di, LIU Zhen, LI Jing, LUO Xiao-Xing, LI Ming-Kai. Synthesis and Antibacterial Activities of Pyran Annulated Heterocyclic Compounds[J]. Chinese Journal of Structural Chemistry,
2015, 34(2): 185-188.
doi:
10.14102/j.cnki.0254-5861.2011-0443
Synthesis and Antibacterial Activities of Pyran Annulated Heterocyclic Compounds
摘要:
Two novel pyran annulated heterocyclic compounds (1 and 2) were synthesized and characterized via IR, 1H NMR and H RMS. The structure of compound 1 was verified by single-crystal X-ray diffraction. The in vitro antibacterial activities of the two compounds against Staphylococcus aureus (S. aureus ATCC 29213), methicillin-resistant S. aureus (MRSA XJ 75302), vancomycin-intermediate S. aureus (Mu50 ATCC 700699), and USA 300 (Los Angeles County clone, LAC) were evaluated by observing the minimum inhibitory concentration.
English
Synthesis and Antibacterial Activities of Pyran Annulated Heterocyclic Compounds
Abstract:
Two novel pyran annulated heterocyclic compounds (1 and 2) were synthesized and characterized via IR, 1H NMR and H RMS. The structure of compound 1 was verified by single-crystal X-ray diffraction. The in vitro antibacterial activities of the two compounds against Staphylococcus aureus (S. aureus ATCC 29213), methicillin-resistant S. aureus (MRSA XJ 75302), vancomycin-intermediate S. aureus (Mu50 ATCC 700699), and USA 300 (Los Angeles County clone, LAC) were evaluated by observing the minimum inhibitory concentration.
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Key words:
- pyran
- / crystal
- / Staphylococcus aureus
- / minimum inhibitory concentration
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