A novel approach for synthesis of 3-amino-5-aryl-2,5-dihydropyridazines using onium salt as soluble support

Meng Gao Cui Fen Lu Gui Chun Yang Zu Xing Chen

引用本文: Meng Gao,  Cui Fen Lu Gui Chun Yang,  Zu Xing Chen. A novel approach for synthesis of 3-amino-5-aryl-2,5-dihydropyridazines using onium salt as soluble support[J]. Chinese Chemical Letters, 2011, 22(7): 823-826. doi: 10.1016/j.cclet.2010.12.055 shu
Citation:  Meng Gao,  Cui Fen Lu Gui Chun Yang,  Zu Xing Chen. A novel approach for synthesis of 3-amino-5-aryl-2,5-dihydropyridazines using onium salt as soluble support[J]. Chinese Chemical Letters, 2011, 22(7): 823-826. doi: 10.1016/j.cclet.2010.12.055 shu

A novel approach for synthesis of 3-amino-5-aryl-2,5-dihydropyridazines using onium salt as soluble support

  • 基金项目:

    We gratefully acknowledge the Natural Sciences Foundation of Hubei province in China (Nos.2007ABA031 and 2008CDA078).

摘要: In this work it was presented an application of task specific onium salt as soluble support for the synthesis of 3-amino-5-ary 1-2,5-dihydropyridazines. This soluble support is of wide applicability and combines advantages of solid phase synthesis without its limitations with those of solution phase chemistry. After a simple washing step, products were cleaved from the supports and obtained in good yields.

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  • 收稿日期:  2010-10-29
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