Microwave-assisted chemoselective copper-catalyzed amination of o-chloro and o-bromobenzoic acids using aromatic amines under solvent free conditions

Yaghoub Sarrafi ,  Manijeh Mohadeszadeh ,  Kamal Alimohammadi

引用本文: Yaghoub Sarrafi,  Manijeh Mohadeszadeh,  Kamal Alimohammadi. Microwave-assisted chemoselective copper-catalyzed amination of o-chloro and o-bromobenzoic acids using aromatic amines under solvent free conditions[J]. Chinese Chemical Letters, 2009, 20(7): 784-788. doi: 10.1016/j.cclet.2009.02.013 shu
Citation:  Yaghoub Sarrafi,  Manijeh Mohadeszadeh,  Kamal Alimohammadi. Microwave-assisted chemoselective copper-catalyzed amination of o-chloro and o-bromobenzoic acids using aromatic amines under solvent free conditions[J]. Chinese Chemical Letters, 2009, 20(7): 784-788. doi: 10.1016/j.cclet.2009.02.013 shu

Microwave-assisted chemoselective copper-catalyzed amination of o-chloro and o-bromobenzoic acids using aromatic amines under solvent free conditions

  • 基金项目:

    We gratefully acknowledge the financial support of this work by the Research Council of Mazandaran University.

摘要: Copper-catalyzed synthesis of N-aryl anthranilic acid derivatives using effective amination of 2-chloro and 2-bromobenzoic acid under microwave irradiation is reported. Some of the advantages of this method are high chemoselectivity, short reaction times, ease of work up procedure and elimination of the need for acid protection.

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  • 收稿日期:  2008-11-12
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