引用本文:
陆鸿飞, 陆明, 章丽娟. 嘌呤2位卤素取代衍生物的合成[J]. 应用化学,
2006, 23(10): 1156-1160.
Citation: LU Hong-Fei, LU Ming, ZHANG Li-Juan. Syntheses of 2-Halogenopurine Derivatives[J]. Chinese Journal of Applied Chemistry, 2006, 23(10): 1156-1160.
Citation: LU Hong-Fei, LU Ming, ZHANG Li-Juan. Syntheses of 2-Halogenopurine Derivatives[J]. Chinese Journal of Applied Chemistry, 2006, 23(10): 1156-1160.
嘌呤2位卤素取代衍生物的合成
English
Syntheses of 2-Halogenopurine Derivatives
Abstract:
A series of 2-halogenopurine derivatives was synthesized from guanine through diazotization.All the products were characterized by 1H NMR,MS and elemental analysis.Fungicidal activities of all the compounds were tested.Good fungicidal activity was observed for 5a,5c,5g and 5h against Bacillus subtillis,5b and 5c against Aspergillus niger,and 5f against Cardida tropicals.Density functions of all the compounds were calculated using Gaussian 98,and the effect of different groups on the net charges of C(2) were discussed.
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Key words:
- purine
- / diazotization
- / synthesis
- / fungicidal activity
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