New synthetic approach for the preparation of 2-aryl-thiazolo[4,5-b]pyridines via Liebeskind-Srogl reaction

Yang-Qiu Peng Lai-Chun Luo Jiao Gong Jian Huang Qi Sun

Citation:  Yang-Qiu Peng, Lai-Chun Luo, Jiao Gong, Jian Huang, Qi Sun. New synthetic approach for the preparation of 2-aryl-thiazolo[4,5-b]pyridines via Liebeskind-Srogl reaction[J]. Chinese Chemical Letters, 2015, 26(8): 1016-1018. doi: 10.1016/j.cclet.2015.05.012 shu

New synthetic approach for the preparation of 2-aryl-thiazolo[4,5-b]pyridines via Liebeskind-Srogl reaction

    通讯作者: Qi Sun,
  • 基金项目:

    This research was supported by the National Natural Science Foundation of China (No. 21272009). (No. 21272009)

摘要: The potentially bioactive 2-aryl-thiazolo[4,5-b]pyridines were synthesized via palladium-catalyzed desulfitative cross-coupling reaction between multisubstituted thiazolo[4,5-b]pyridine thioethers and boronic acids. Yields of 48%-94% were obtained with copper(I) thiophene-2-carboxylate in the system.

English

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  • 发布日期:  2015-05-15
  • 收稿日期:  2015-03-18
  • 网络出版日期:  2015-04-17
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