A novel and facile synthesis of 4-arylquinolin-2(1H)-ones under metal-free conditions
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关键词:
- 4-Arylquinolin-2(1H)-one
- / Metal-free
- / Selectfluor
- / Synthesis
English
A novel and facile synthesis of 4-arylquinolin-2(1H)-ones under metal-free conditions
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Key words:
- 4-Arylquinolin-2(1H)-one
- / Metal-free
- / Selectfluor
- / Synthesis
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[3] (a) T.N. Glasnov, W. Stadlbauer, C.O. Kappe, Microwave-assisted multistep synthesis of functionalized 4-arylquinolin-2(1H)-ones using palladium-catalyzed cross-coupling chemistry, J. Org. Chem. 70 (2005) 3864-3870; (b) P. Hewawasam, W. Fan, J. Knipe, et al., The synthesis and structure-activity relationships of 4-aryl-3-aminoquinolin-2-ones: a new class of calcium-dependent, large conductance, potassium (maxi-K) channel openers targeted for poststroke neuroprotection, Bioorg. Med. Chem. Lett. 12 (2002) 1779-1783.[3] (a) T.N. Glasnov, W. Stadlbauer, C.O. Kappe, Microwave-assisted multistep synthesis of functionalized 4-arylquinolin-2(1H)-ones using palladium-catalyzed cross-coupling chemistry, J. Org. Chem. 70 (2005) 3864-3870; (b) P. Hewawasam, W. Fan, J. Knipe, et al., The synthesis and structure-activity relationships of 4-aryl-3-aminoquinolin-2-ones: a new class of calcium-dependent, large conductance, potassium (maxi-K) channel openers targeted for poststroke neuroprotection, Bioorg. Med. Chem. Lett. 12 (2002) 1779-1783.
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[5] D.V. Kadnikov, R.C. Larock, Synthesis of 2-quinolones via palladium-catalyzed carbonylative annulation of internal alkynes by N-substituted o-iodoanilines, J. Org. Chem. 69 (2004) 6772-6780.[5] D.V. Kadnikov, R.C. Larock, Synthesis of 2-quinolones via palladium-catalyzed carbonylative annulation of internal alkynes by N-substituted o-iodoanilines, J. Org. Chem. 69 (2004) 6772-6780.
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[6] (a) D.J. Tang, B.X. Tang, J.H. Li, Selective synthesis of 3-aryl quinolin-2(1H)-ones and 3-(1-arylmethylene)oxindoles involving a 2-fold arene C-H activation process, J. Org. Chem. 74 (2009) 6749-6755; (b) P. Xie, Z.Q. Wang, G.B. Deng, et al., Copper-catalyzed aerobic oxidative carbocyclization-ketonization cascade: selective synthesis of quinolinones, Adv. Synth. Catal. 355 (2013) 2257-2262.[6] (a) D.J. Tang, B.X. Tang, J.H. Li, Selective synthesis of 3-aryl quinolin-2(1H)-ones and 3-(1-arylmethylene)oxindoles involving a 2-fold arene C-H activation process, J. Org. Chem. 74 (2009) 6749-6755; (b) P. Xie, Z.Q. Wang, G.B. Deng, et al., Copper-catalyzed aerobic oxidative carbocyclization-ketonization cascade: selective synthesis of quinolinones, Adv. Synth. Catal. 355 (2013) 2257-2262.
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[9] W.P. Mai, G.C. Sun, J.T. Wang, et al., Silver-catalyzed radical tandem cyclization: an approach to direct synthesis of 3-acyl-4-arylquinolin-2(1H)-ones, J. Org. Chem. 79 (2014) 8094-8102.[9] W.P. Mai, G.C. Sun, J.T. Wang, et al., Silver-catalyzed radical tandem cyclization: an approach to direct synthesis of 3-acyl-4-arylquinolin-2(1H)-ones, J. Org. Chem. 79 (2014) 8094-8102.
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[10] L. Shi, D. Zhang, R. Lin, et al., The direct C-H halogenations of indoles, Tetrahedron Lett. 55 (2014) 2243-2245.[10] L. Shi, D. Zhang, R. Lin, et al., The direct C-H halogenations of indoles, Tetrahedron Lett. 55 (2014) 2243-2245.
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