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Electro-catalyzed multicomponent transformation of 3-methyl-1-phenyl-1H-pyrazol-5(4H)-one to 1,4-dihydropyrano[2,3-c]pyrazole derivatives in green medium

Zahra Vafajoo ,  Nourallah Hazeri ,  Malek Taher Maghsoodlou ,  Hojat Veisi

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Citation:  Zahra Vafajoo, Nourallah Hazeri, Malek Taher Maghsoodlou, Hojat Veisi. Electro-catalyzed multicomponent transformation of 3-methyl-1-phenyl-1H-pyrazol-5(4H)-one to 1,4-dihydropyrano[2,3-c]pyrazole derivatives in green medium[J]. Chinese Chemical Letters, 2015, 26(8): 973-976. doi: 10.1016/j.cclet.2015.04.016 shu

Electro-catalyzed multicomponent transformation of 3-methyl-1-phenyl-1H-pyrazol-5(4H)-one to 1,4-dihydropyrano[2,3-c]pyrazole derivatives in green medium

    • 通讯作者: Zahra Vafajoo,
    Nourallah Hazeri,
摘要: An efficient and convenient synthesis of 1,4-dihydropyrano[2,3-c]pyrazole derivatives is described, using the electrogenerated anion of ethanol as the base in the presence of sodium bromide as an supporting electrolyte in a one-pot, three component condensation of malononitrile, aromatic aldehydes and 3-methyl-1-phenyl-1H-pyrazol-5(4H)-one. The reaction is carried out in an undivided cell containing an iron electrode as the cathode and a graphite electrode as the anode, at a constant current at room temperature.

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  • 发布日期:  2015-04-18
  • 收稿日期:  2015-02-01
  • 网络出版日期:  2015-03-19
通讯作者: 陈斌, bchen63@163.com
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