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Facile one-pot synthesis of PEGylated monodisperse mesoporous silica nanoparticles with controllable particle sizes

Quan Zhang ,  Zhou Ye ,  Shu-Ting Wang ,  Jian Yin

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Citation:  Quan Zhang, Zhou Ye, Shu-Ting Wang, Jian Yin. Facile one-pot synthesis of PEGylated monodisperse mesoporous silica nanoparticles with controllable particle sizes[J]. Chinese Chemical Letters, 2014, 25(2): 257-260. shu

Facile one-pot synthesis of PEGylated monodisperse mesoporous silica nanoparticles with controllable particle sizes

    • 通讯作者: Quan Zhang,
    Jian Yin,
摘要: In this work, we describe the one-pot synthesis of PEGylated mesoporous silica nanoparticles (MSNs) with uniform shape, tunable sizes, and narrow size distributions. The size of these nanoparticles can be controlled from 49 nmto 98 nmby simply varying the concentration of triethanolamine during the basecatalyzed sol-gel reaction. Particles were characterized by transmission electron microscopy, dynamic light scattering, Fourier transform infrared spectrometry, thermogravimetric analysis, and nitrogen adsorption-desorption measurements. These PEGylated MSNs exhibited excellent long-term stability in biological media, which ensures their potential applications in drug delivery.

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  • 收稿日期:  2013-06-04
  • 网络出版日期:  2013-10-23
通讯作者: 陈斌, bchen63@163.com
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