1H-15N HMBC spectra of C18-diterpenoid alkaloids

Qian Mei Yao-Nan Wang Ming Zhao Xiao-Yu Liu Shi-Qi Peng Feng-Peng Wang

Citation:  Qian Mei, Yao-Nan Wang, Ming Zhao, Xiao-Yu Liu, Shi-Qi Peng, Feng-Peng Wang. 1H-15N HMBC spectra of C18-diterpenoid alkaloids[J]. Chinese Chemical Letters, 2015, 26(6): 804-806. doi: 10.1016/j.cclet.2015.04.028 shu

1H-15N HMBC spectra of C18-diterpenoid alkaloids

    通讯作者: Ming Zhao,
    Feng-Peng Wang,
  • 基金项目:

    We are grateful the National Natural Science Foundation of China (No. 81273387) for the financial support of this research. (No. 81273387)

摘要: The normally underused 1H-15N HMBC spectra of thirteen C18-diterpenoid alkaloids have been determined for the first time. As a result, the significant effects of the substituents of nitrogen atoms, the conformations of A ring, and protonation, on the nitrogen-15 chemical shifts are demonstrated.

English

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    1. [1] R.M. Silverstein, F.X. Webster, D.J. Kiemle, Spectrometric Identification of Organic Compounds, 7th ed., John Wiley & Sons, New York, 2005, pp. 317-326.[1] R.M. Silverstein, F.X. Webster, D.J. Kiemle, Spectrometric Identification of Organic Compounds, 7th ed., John Wiley & Sons, New York, 2005, pp. 317-326.

    2. [2] R. Marek, O. Humpa, J. Dostál, J. Slavík, V. Sklenár, 15N NMR study of isoquinoline alkaloids, Magn. Reson. Chem. 37 (1999) 195-202.[2] R. Marek, O. Humpa, J. Dostál, J. Slavík, V. Sklenár, 15N NMR study of isoquinoline alkaloids, Magn. Reson. Chem. 37 (1999) 195-202.

    3. [3] G.E. Martin, M. Solntsevan, A.J. Williams, Applications of 15N NMR spectroscopy in alkaloid chemistry, in: E. Fattorusso, O. Taglialatela-Scafati (Eds.), Modern Alkaloids: Structure, Isolation, Synthesis and Biology, Wiley-VCH Verlag, Weinheim, 2008, pp. 403-471.[3] G.E. Martin, M. Solntsevan, A.J. Williams, Applications of 15N NMR spectroscopy in alkaloid chemistry, in: E. Fattorusso, O. Taglialatela-Scafati (Eds.), Modern Alkaloids: Structure, Isolation, Synthesis and Biology, Wiley-VCH Verlag, Weinheim, 2008, pp. 403-471.

    4. [4] Q.F. Chen, Y.N. Wang, L. Wang, et al., Full assignments of the 1H, 13C and 15N magnetic resonance spectra of two porphyrin compounds, Nat. Prod. Commun. 9 (2014) 547-550.[4] Q.F. Chen, Y.N. Wang, L. Wang, et al., Full assignments of the 1H, 13C and 15N magnetic resonance spectra of two porphyrin compounds, Nat. Prod. Commun. 9 (2014) 547-550.

    5. [5] F.P. Wang, D.L. Chen, H.Y. Deng, et al., Further revisions on the diterpenoid alkaloids reported in a JNP paper (2012, 75, 1145-1159), Tetrahedron 70 (2014) 2582-2590.[5] F.P. Wang, D.L. Chen, H.Y. Deng, et al., Further revisions on the diterpenoid alkaloids reported in a JNP paper (2012, 75, 1145-1159), Tetrahedron 70 (2014) 2582-2590.

    6. [6] F.P. Wang, Q.H. Chen, X.T. Liang, The C18-diterpenoid alkaloids, in: G.A. Cordell (Ed.), The Alkaloids, vol. 67, Elsevier, San Diego, 2009, pp. 1-78.[6] F.P. Wang, Q.H. Chen, X.T. Liang, The C18-diterpenoid alkaloids, in: G.A. Cordell (Ed.), The Alkaloids, vol. 67, Elsevier, San Diego, 2009, pp. 1-78.

    7. [7] C.S. Peng, J.Z. Wang, X.X. Jian, F.P. Wang, Alkaloids of Aconitum sinomontanum and Aconitum racemulosum Franch var. pengzhouense, Nat. Prod. Res. Dev. 12 (2000) 45-51.[7] C.S. Peng, J.Z. Wang, X.X. Jian, F.P. Wang, Alkaloids of Aconitum sinomontanum and Aconitum racemulosum Franch var. pengzhouense, Nat. Prod. Res. Dev. 12 (2000) 45-51.

    8. [8] F.P. Wang, C.S. Peng, X.X. Jian, D.L. Chen, Five new norditerpenoid alkaloids from Aconitum sinomontanum, J. Asian Nat. Prod. Res. 3 (2001) 15-22.[8] F.P. Wang, C.S. Peng, X.X. Jian, D.L. Chen, Five new norditerpenoid alkaloids from Aconitum sinomontanum, J. Asian Nat. Prod. Res. 3 (2001) 15-22.

    9. [9] C.S. Peng, D.L. Chen, Q.H. Chen, F.P. Wang, New diterpenoid alkaloids from roots of Aconitum sinomontanum, Chin. J. Org. Chem. 25 (2005) 1235-1239.[9] C.S. Peng, D.L. Chen, Q.H. Chen, F.P. Wang, New diterpenoid alkaloids from roots of Aconitum sinomontanum, Chin. J. Org. Chem. 25 (2005) 1235-1239.

    10. [10] Y. He, Studies on the Alkaloidal Components from Delphinium bonvalotii, (M.S. thesis), Sichuan University, Chengdu, 2006.[10] Y. He, Studies on the Alkaloidal Components from Delphinium bonvalotii, (M.S. thesis), Sichuan University, Chengdu, 2006.

    11. [11] L. Song,X.X. Liang,D.L. Chen, X.X. Jian,F.P.Wang,New C18-diterpenoid alkaloids from Delphinium anthriscifolium var. savatieri, Chem. Pharm. Bull. 55 (2007) 918-921.[11] L. Song,X.X. Liang,D.L. Chen, X.X. Jian,F.P.Wang,New C18-diterpenoid alkaloids from Delphinium anthriscifolium var. savatieri, Chem. Pharm. Bull. 55 (2007) 918-921.

    12. [12] F.P. Wang, Q.H. Chen, The C19-diterpenoid alkaloids, in: G.A. Cordell (Ed.), The Alkaloids: Chemistry and Biology, vol. 69, Elsevier Science, New York, 2010, pp. 1-577.[12] F.P. Wang, Q.H. Chen, The C19-diterpenoid alkaloids, in: G.A. Cordell (Ed.), The Alkaloids: Chemistry and Biology, vol. 69, Elsevier Science, New York, 2010, pp. 1-577.

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  • 发布日期:  2015-04-18
  • 收稿日期:  2014-12-23
  • 网络出版日期:  2015-03-27
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