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Propylphosphonic anhydride (T3P®) catalyzed one-pot synthesis of α-aminonitriles

Sirigireddy Sudharsan Reddy ,  Bhoomireddy Rajendra Prasad Reddy ,  Peddiahgari Vasu Govardhana Reddy

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Citation:  Sirigireddy Sudharsan Reddy, Bhoomireddy Rajendra Prasad Reddy, Peddiahgari Vasu Govardhana Reddy. Propylphosphonic anhydride (T3P®) catalyzed one-pot synthesis of α-aminonitriles[J]. Chinese Chemical Letters, 2015, 26(6): 739-743. doi: 10.1016/j.cclet.2015.03.021 shu

Propylphosphonic anhydride (T3P®) catalyzed one-pot synthesis of α-aminonitriles

    • 通讯作者: Peddiahgari Vasu Govardhana Reddy,
摘要: The Strecker reaction was performed via a one-pot three component condensation of hetero aromatic/aromatic aldehydes, secondary amines and trimetylsilyl cyanide in the presence of propylphosphonic anhydride (T3P®) to accomplish the corresponding α-aminonitriles. The main advantages of this method are very short reaction time and excellent yields.

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  • 发布日期:  2015-03-28
  • 收稿日期:  2014-11-30
  • 网络出版日期:  2015-02-05
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