引用本文:
Jian Ya LING, Qin Zheng YANG, Shan Shan LUO, Yan LI, Chang Kai ZHANG. Preliminary Study on Cordycepin-DNA Interaction by Raman Spectroscopy[J]. Chinese Chemical Letters,
2005, 16(1): 71-74.
Citation: Jian Ya LING, Qin Zheng YANG, Shan Shan LUO, Yan LI, Chang Kai ZHANG. Preliminary Study on Cordycepin-DNA Interaction by Raman Spectroscopy[J]. Chinese Chemical Letters, 2005, 16(1): 71-74.
Citation: Jian Ya LING, Qin Zheng YANG, Shan Shan LUO, Yan LI, Chang Kai ZHANG. Preliminary Study on Cordycepin-DNA Interaction by Raman Spectroscopy[J]. Chinese Chemical Letters, 2005, 16(1): 71-74.
Preliminary Study on Cordycepin-DNA Interaction by Raman Spectroscopy
摘要:
The interaction of cordycepin with calf thymus DNA was investigated at physiological pH with drug/DNA molar ratio of 8. The Raman spectroscopy results indicated that the intercalation of high concentration cordycepin and the interaction of cordycepin with PO2 group led to a major reduction of B-form DNA structure in favor of A-form DNA.
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关键词:
- Cordycepin
- / calf thymus DNA
- / Raman spectroscopy
- / conformation.
English
Preliminary Study on Cordycepin-DNA Interaction by Raman Spectroscopy
Abstract:
The interaction of cordycepin with calf thymus DNA was investigated at physiological pH with drug/DNA molar ratio of 8. The Raman spectroscopy results indicated that the intercalation of high concentration cordycepin and the interaction of cordycepin with PO2 group led to a major reduction of B-form DNA structure in favor of A-form DNA.
-
Key words:
- Cordycepin
- / calf thymus DNA
- / Raman spectroscopy
- / conformation.
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