引用本文:
Fend Peng WANG, Ju Zheng FAN, Zheng Bang LI, Jin Song YANG, Bo Gang LI. Modifications of Norditerpenoid Alkaloids:Ⅰ.N-Deethylation Reactions[J]. Chinese Chemical Letters,
1999, 10(5): 375-378.
Citation: Fend Peng WANG, Ju Zheng FAN, Zheng Bang LI, Jin Song YANG, Bo Gang LI. Modifications of Norditerpenoid Alkaloids:Ⅰ.N-Deethylation Reactions[J]. Chinese Chemical Letters, 1999, 10(5): 375-378.
Citation: Fend Peng WANG, Ju Zheng FAN, Zheng Bang LI, Jin Song YANG, Bo Gang LI. Modifications of Norditerpenoid Alkaloids:Ⅰ.N-Deethylation Reactions[J]. Chinese Chemical Letters, 1999, 10(5): 375-378.
Modifications of Norditerpenoid Alkaloids:Ⅰ.N-Deethylation Reactions
摘要:
Usine oxidation with KMnO4. KMnO4/acetonc-H2O, NBS. followed by Polonovsky reaction and imine formation. the N-deethylatiun of sit norditerpenoid alkaloids 6-epi-forsticine yunnaconitine, 3,13-diacetylyunnacunitine, 13-dehydry-indacunitine, indacunitinc and acetylpseudaconine are reported in 36-60% yields.
English
Modifications of Norditerpenoid Alkaloids:Ⅰ.N-Deethylation Reactions
Abstract:
Usine oxidation with KMnO4. KMnO4/acetonc-H2O, NBS. followed by Polonovsky reaction and imine formation. the N-deethylatiun of sit norditerpenoid alkaloids 6-epi-forsticine yunnaconitine, 3,13-diacetylyunnacunitine, 13-dehydry-indacunitine, indacunitinc and acetylpseudaconine are reported in 36-60% yields.
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Key words:
- Norditerpenpid alkaloids
- / N-deethy lation
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