引用本文:
黎虹颖, 古宁宇, 唐纪琳. 基于原子力显微镜的单分子力谱在生物研究中的应用[J]. 应用化学,
2012, 29(12): 1356-1363.
doi:
10.3724/SP.J.1095.2012.20210
Citation: LI Hongying, GU Ningyu, TANG Jilin. Application of Atomic Force Microscopy Based Single Molecule Force Spectroscopy in Biological Research[J]. Chinese Journal of Applied Chemistry, 2012, 29(12): 1356-1363. doi: 10.3724/SP.J.1095.2012.20210
Citation: LI Hongying, GU Ningyu, TANG Jilin. Application of Atomic Force Microscopy Based Single Molecule Force Spectroscopy in Biological Research[J]. Chinese Journal of Applied Chemistry, 2012, 29(12): 1356-1363. doi: 10.3724/SP.J.1095.2012.20210
基于原子力显微镜的单分子力谱在生物研究中的应用
English
Application of Atomic Force Microscopy Based Single Molecule Force Spectroscopy in Biological Research
Abstract:
Atomic force microscopy(AFM) is widely used in biological research,AFM based single molecule force spectroscopy can be applied to study the intramolecular and intermolecular interactions of biomolecules at the single-molecule and single-cell levels.In this paper,we present the latest progress of AFM based single molecule force spectroscopy in biomolecular interaction,protein unfolding,cell surface biomolecules,cell mechanical properties and single molecule force spectroscopy imaging.
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Key words:
- atomic force microscopy
- / single molecule force spectroscopy
- / protein
- / cell
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