A green multicomponent synthesis of bioactive pyrimido[4, 5-b]quinoline derivatives as antibacterial agents in water catalyzed by RuCl3·xH2O

Citation: Khalil Tabatabaeian, Abdollah Fallah Shojaei, Farhad Shirini, Seyyedeh Zoha Hejazi, Mehdi Rassa. A green multicomponent synthesis of bioactive pyrimido[4, 5-b]quinoline derivatives as antibacterial agents in water catalyzed by RuCl₃·xH₂O[J]. Chinese Chemical Letters, 2014, 25(2): 308-312. shu

A green multicomponent synthesis of bioactive pyrimido[4, 5-b]quinoline derivatives as antibacterial agents in water catalyzed by RuCl₃·xH₂O

通讯作者: Khalil Tabatabaeian,

摘要: An efficient, convenient and environmentally benign one-pot multicomponent reaction for the preparation of pyrimido[4,5-b]quinoline derivatives as biologically, pharmacologically and antibacterially active products has been developed using RuCl₃·xH₂O as a reusable homogenous catalyst. Use of water as a green solvent, purification of products by non-chromatographic methods, reusability of transition metal homogenous catalyst, saving energy by employing multicomponent reactions, short reaction times and high yields, are some of the advantages of this process.

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English

A green multicomponent synthesis of bioactive pyrimido[4, 5-b]quinoline derivatives as antibacterial agents in water catalyzed by RuCl₃·xH₂O

1.
a Department of Chemistry, College of Science, University of Guilan, Rasht 41335-1914, Iran;
2.
b Department of Biology, College of Science, University of Guilan, Rasht 41335-1914, Iran

Corresponding author: Khalil Tabatabaeian,

Received Date: 15 August 2013

Abstract: An efficient, convenient and environmentally benign one-pot multicomponent reaction for the preparation of pyrimido[4,5-b]quinoline derivatives as biologically, pharmacologically and antibacterially active products has been developed using RuCl₃·xH₂O as a reusable homogenous catalyst. Use of water as a green solvent, purification of products by non-chromatographic methods, reusability of transition metal homogenous catalyst, saving energy by employing multicomponent reactions, short reaction times and high yields, are some of the advantages of this process.

Key words:

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1.
沈阳化工大学材料科学与工程学院沈阳 110142

A green multicomponent synthesis of bioactive pyrimido[4, 5-b]quinoline derivatives as antibacterial agents in water catalyzed by RuCl₃·xH₂O

通讯作者: Khalil Tabatabaeian,

English

A green multicomponent synthesis of bioactive pyrimido[4, 5-b]quinoline derivatives as antibacterial agents in water catalyzed by RuCl₃·xH₂O

Corresponding author: Khalil Tabatabaeian,

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