Synthesis, Characterization and Biological Activities of Novel Water-soluble Metalloporphyrins

Zao Ying LI ,  Yue Ning ZHANG ,  Zhen Ting GAO ,  Yi LIU ,  Xun Jin ZHU

引用本文: Zao Ying LI,  Yue Ning ZHANG,  Zhen Ting GAO,  Yi LIU,  Xun Jin ZHU. Synthesis, Characterization and Biological Activities of Novel Water-soluble Metalloporphyrins[J]. Chinese Chemical Letters, 2001, 12(12): 1085-1088. shu
Citation:  Zao Ying LI,  Yue Ning ZHANG,  Zhen Ting GAO,  Yi LIU,  Xun Jin ZHU. Synthesis, Characterization and Biological Activities of Novel Water-soluble Metalloporphyrins[J]. Chinese Chemical Letters, 2001, 12(12): 1085-1088. shu

Synthesis, Characterization and Biological Activities of Novel Water-soluble Metalloporphyrins

  • 基金项目:

    Financial support from the National Natural Science Foundation of China is gratefully acknowledged (No.29972035).

摘要: The synthesis, characterization, and biological activities of a series of metal porphyrins were described. The complexes 3a~3e were prepared from the reaction of compound 2 with M(OAc)2 in CHCl3, and the treatment of 3a~3f with pyridine gave corresponding complexes 4a~4f. These new compounds were identified by absorption spectroscopies, 1H NMR and elemental analysis. The results of biological activity testing revealed that 4a and 4c had stronger inhibiting action for Escherichia coli (CCTCC AB91115).

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  • 收稿日期:  2001-04-20
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