引用本文:
Mei DU, Sheng JIN, Zhen Quan GUO. A New Competitive Inhibitory Monoclonal Antibody to Carboxypcptidase A (CPA)[J]. Chinese Chemical Letters,
1999, 10(2): 121-122.
Citation: Mei DU, Sheng JIN, Zhen Quan GUO. A New Competitive Inhibitory Monoclonal Antibody to Carboxypcptidase A (CPA)[J]. Chinese Chemical Letters, 1999, 10(2): 121-122.
Citation: Mei DU, Sheng JIN, Zhen Quan GUO. A New Competitive Inhibitory Monoclonal Antibody to Carboxypcptidase A (CPA)[J]. Chinese Chemical Letters, 1999, 10(2): 121-122.
A New Competitive Inhibitory Monoclonal Antibody to Carboxypcptidase A (CPA)
摘要:
The monoclonal antibody ID11D7 to carboxypeptidase A (CPA) was prepared. The inhibitory effect of McAb ID11D7 on the peptidase activity of CPA was measured. The result reflects that the McAb ID11D7 can competitively inhibit the peptidase activity of CPA with an apparent inhibitory constant of 6.3 × 10-9M. Based on this work, the McAb ID11D7 can be used as idiotypic antigen to prepare anti-idiotypic catalytic antibody with the peptidase activity similar to CPA.
English
A New Competitive Inhibitory Monoclonal Antibody to Carboxypcptidase A (CPA)
Abstract:
The monoclonal antibody ID11D7 to carboxypeptidase A (CPA) was prepared. The inhibitory effect of McAb ID11D7 on the peptidase activity of CPA was measured. The result reflects that the McAb ID11D7 can competitively inhibit the peptidase activity of CPA with an apparent inhibitory constant of 6.3 × 10-9M. Based on this work, the McAb ID11D7 can be used as idiotypic antigen to prepare anti-idiotypic catalytic antibody with the peptidase activity similar to CPA.
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