引用本文:
Yan Guang WANG, Jian Lin PAN, Yao Zu CHEN. Synthesis and Antitumor Activity of New Derivatives of Podophyllotoxin[J]. Chinese Chemical Letters,
1996, 7(11): 987-988.
Citation: Yan Guang WANG, Jian Lin PAN, Yao Zu CHEN. Synthesis and Antitumor Activity of New Derivatives of Podophyllotoxin[J]. Chinese Chemical Letters, 1996, 7(11): 987-988.
Citation: Yan Guang WANG, Jian Lin PAN, Yao Zu CHEN. Synthesis and Antitumor Activity of New Derivatives of Podophyllotoxin[J]. Chinese Chemical Letters, 1996, 7(11): 987-988.
Synthesis and Antitumor Activity of New Derivatives of Podophyllotoxin
摘要:
A series of analogues of etoposide(VP-16),the C-4 alkylamino-substituted 4'-demethyl-epipodophyllotoxins,have been synthesized and studied for their activity to inhibit L1210 and KB cells in vitro.Most new compounds are as active or more active than VP-16 in their inhibition of both L1210 and KB cells.
English
Synthesis and Antitumor Activity of New Derivatives of Podophyllotoxin
Abstract:
A series of analogues of etoposide(VP-16),the C-4 alkylamino-substituted 4'-demethyl-epipodophyllotoxins,have been synthesized and studied for their activity to inhibit L1210 and KB cells in vitro.Most new compounds are as active or more active than VP-16 in their inhibition of both L1210 and KB cells.
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